How you lay out your grid changes what you can ask about it. Here is what actually helps, in practice.

Optimal parameters: (1) Clear cell separation: 6–10px gaps, visible borders even better, (2) Logical layout: reading order (L→R, T→B), most important image top-left, (3) Consistent cell dimensions: uniform cells keep the arrangement predictable, (4) Resolution: export at 2048px on the longest side.

Prompt structure matters as much: always describe the grid layout, identify cell contents, then ask your question. This three-part structure (layout → content → question) consistently produces higher-quality responses.

For sequential analysis: Strip of 3 or 1×4 horizontal strip with numbered cells. For comparison: side-by-side 1×2. For multi-dimensional: 2×2 with dimensions as rows, variants as columns.